Table 1.
Mouse Strain | Severity of Defect* |
|||
---|---|---|---|---|
Age (mo) | No Defect | Mild Defect | Severe Defect | |
CD36−/− knockout* | 2–6 | 31 | 2 | 1 |
8–11 | 22 | 11 | 3 | |
16 | 0 | 12 | 8† | |
TSP1−/− knockout‡ | 2–6 | 40 | 0 | 0 |
8–11 | 43 | 0 | 0 | |
TLR2−/− knockout§ | 19–25 | 8 | 0 | 0 |
Data presented in Figure 1 and summarized here, n = 90.
Frequency of severe defects was compared using Fisher's exact test between (1) CD36−/− mice 16 months old with TLR2−/− mice 19–25 years old (P = 6.4 × 10−7), and (2) CD36−/− mice 8–11 months old with TSP1−/− mice 8–11 months old (P = 3.1 × 10−6).
n = 83.
n = 8.