Figure 2.

Differential Distribution of macrophages in normal pregnancy and pregnancy complicated with preeclamsia and IUGR. While in normal pregnancies macrophages are located in the stroma surrounding the transformed spiral arteries and extravillous trophoblast (A) ; in pre-eclampsia macrophages are located within and around the spiral arteries separating them from the trophoblast cells (B). In the normal condition, macrophages promote trophoblast survival; while in the pathologic state induce apoptosis