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. 2011 Mar 10;6(3):e17568. doi: 10.1371/journal.pone.0017568

Figure 5. Multiple sequence alignments of remotely conserved domains found in proteins associated with human diseases.

Figure 5

(A) Multiple sequence alignment of the AKAP10 family with the CUT-like HLH domain family. (B) Multiple sequence alignment of the Lba protein family with the VHS domain family. Residues that are conserved between the two families are highlighted in yellow, those found in only one of them are highlighted in blue and green, respectively. Essential, functional residues retrieved from the CD database are indicated by hash keys. Accession numbers of sequences can be found in Supplemental Table S7.