Table 1. Frequency of mgRb:Rb−/−:p130−/− embryos recovered.
Gestation | mgRb:Rb−/− * | mgRb:Rb−/−:p130−/− * | mgRb:Rb−/−:p130−/− ** |
E14.5 | 4/54 (7.41%) | 6/54 (11.11%) | Not determined |
E15.5 | 8/41 (19.51%) | 6/41 (14.63%) | 6/38 (15.79%) |
E16.5 | 11/53 (20.75%) | 6/53 (11.32%) | 2/20 (10.0%) |
E17.5 | 9/59 (24.09%) | 1/59 (1.69%) | 4/45 (8.89%) |
*Mutant embryos obtained from mgRb:Rb+/−:p130+/− × mgRb:Rb+/−:p130−/− intercrosses. Total of 5 in utero deaths at E17.5 were not included. A frequency of 12.5% is expected in each indicated group.
**Mutant embryos obtained from mgRb:Rb+/−:p130−/− × mgRb:Rb+/−:p130−/− intercrosses. Total of 4 in utero deaths at E17.5 were not included. A frequency of 25% is expected in mgRb:Rb−/−:p130−/− group.