Table 2. List of cell cycle related genes modulated by EBV Rta in 293 and NPC-TW01 cells.

Gene Symbol	293TetER	TW01TetER	Gene Description
CCND1	−3.1#	−1.1	cyclin D1
CCND2	−3.1	−3.3	cyclin D2
CDK4	−1.3	−2.2	cyclin-dependent kinase 4
CDK6	−1.8	−1.1	cyclin-dependent kinase 6
CDKN1A	2.2	1.0	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHEK2	−1.2	−1.9	CHK2 checkpoint homolog (S. pombe)
GNL3	−2.0	−2.1	guanine nucleotide binding protein-like 3 (nucleolar)
H1F0	3.8	2.4	H1 histone family, member 0
HERC5	2.2	1.9	hect domain and RLD 5
HEXIM1	2.3	1.3	hexamethylene bis-acetamide inducible 1
HSPA2	2.8	2.3	heat shock 70kDa protein 2
IFITM1	5.0	1.8	interferon induced transmembrane protein 1
LMLN	1.9	2.2	leishmanolysin-like, metallopeptidase M8 family
MYC	−3.0	−4.5	v-myc myelocytomatosis viral oncogene homolog
NEFH	6.6	1.3	neurofilament, heavy polypeptide
NEFL	−2.3	−3.1	neurofilament, light polypeptide
NOLC1	−1.8	−2.4	nucleolar and coiled-body phosphoprotein 1
PTTG2	1.1	2.0	pituitary tumor-transforming 2
RRS1	−2.6	−2.5	RRS1 ribosome biogenesis regulator
SFN	14.3	1.6	stratifin (14-3-3σ)
TGFB2	−2.1	−1.3	transforming growth factor, beta 2
FASN##	2.2	2.2	fatty acid synthase
MERTK##	8.3	21.5	c-mer proto-oncogene tyrosine kinase

^#: Fold-change compared to the control groups. Details for the experimental design and data process procedures are referred to Gene Expression Omnibus (GEO) under accession number GSE24587.

^##: Also observed in primary keratinocytes transduced by adenovirus vector expressing Rta [32], [33].