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. Author manuscript; available in PMC: 2012 Mar 9.
Published in final edited form as: Nano Lett. 2011 Jan 31;11(3):1383–1388. doi: 10.1021/nl200116d

Figure 1.

Figure 1

Experimental setup and proposed model for the formation of mineralized collagen fibrils. Amorphous calcium phosphate formed inside or near the exit of the nanopores simultaneously with the self-assembly of collagen fibrils. The fibrils were extruded from the pores in the direction of the feed solution flow. The upper inset is a transmission electron micrograph of the mineralized collagen fibrils showing visual enhancement of the periodic banding structure as a result of the incorporation of CaP. The lower inset is a scanning electron micrograph of the collagen fibrils showing the overgrowth of CaP.