Fig. 4.

Increased protein expression of p21^Waf1/Cip1, p27^Kip1, and p15^INK4B and decreased protein expression of cyclin D3 upon treatment with DTX-κ. This figure shows a representative image from Western blot analysis and relative protein expression levels of p21^Waf1/Cip1 (A), p27^Kip1 (B), p15^INK4B (C), and cyclin D3 (D). The protein expression levels were normalized to that of β-actin. Furthermore, data were normalized to the values obtained for the control group and presented as means ± SE (control group: n = 2, DTX-κ group: n = 6; ^*p < 0.05).