Effect of pharmacological inhibitors on force measurements during uniaxial tissue stretch. A: Representative force measurement curves for inhibitors compared with controls. B: Mean ± SE equilibrium tissue force across experimental conditions. Equilibrium tissue force was significantly different among the groups (ANOVA, F=8.00, p<.001, N=28 mice). Individual comparisons using Fisher’s LSD showed that sodium azide, colchicine and Rho kinase inhibitor were significantly different from control and Rac-1 inhibitor, but were not significantly different from each other. Means sharing a common letter are not significantly different (Fisher’s LSD).