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. Author manuscript; available in PMC: 2012 Mar 15.
Published in final edited form as: Fertil Steril. 2011 Jan 14;95(4):1256–1260. doi: 10.1016/j.fertnstert.2010.12.048

Figure 1.

Figure 1

Celecoxib treatment reduces oocyte nuclear maturation. Oocytes were obtained from monkeys experiencing controlled ovarian stimulation after treatment for 36 hours with either hCG alone (dark bars; n=12 monkeys) or hCG and the COX2 inhibitor celecoxib (light bars; n=6 monkeys). Oocytes were assessed for nuclear status (germinal vesicle intact (GV), germinal vesicle break down (GVBD), or presence of a single polar body (MII)) by light microscopy. Data are expressed as the percent of total cohort of oocytes which are at the indicated stage. Within each class of oocytes, differences between treatment groups are indicated with an asterisk (*) as determined by unpaired t-test, p<0.05. For oocytes from animals receiving hCG alone, b>a as determined by ANOVA and Newman-Keuls’ test, p<0.05.