Table 2.

Mean HDL-C (mg/dl) Levels per copy of the Minor Allele at Significant SNPs in the Entire Cohort and Across Median levels of Physical Activity

				Mean (SD) HDL-C per allele, copy mg/dl
SNP	Chromosome, Gene		N	0	1	2	β (SE)	P
rs10096633	8p21, LPL	All women	22,938	53.3 (15.0)	55.0 (15.3)	55.9 (15.2)	1.6 (0.2)	<0.0001
		≤8.8MET-hours/week	11,445	51.5 (14.4)	53.9 (14.9)	54.1 (14.6)	2.1 (0.3)	<0.0001
		>8.8MET-hours/week	11,493	55.2 (15.2)	56.1 (15.6)	57.7 (15.6)	1.0 (0.3)	<0.001
		Test for interaction						0.004
rs1800588	15q22, LIPC	All women	22,936	52.9 (14.6)	54.9 (15.5)	56.9 (15.5)	2.0 (0.2)	<0.0001
		≤8.8MET-hours/week	11,445	51.3 (14.2)	53.0 (15.1)	54.4 (14.3)	1.7 (0.2)	<0.0001
		>8.8MET-hours/week	11,491	54.4 (14.9)	56.8 (15.7)	59.3 (16.3)	2.3 (0.2)	<0.0001
		Test for interaction						0.04
rs1532624	16q13, CETP	All women	22,195	51.3 (14.2)	54.1 (15.0)	57.5 (15.7)	3.0 (0.1)	<0.0001
		≤8.8MET-hours/week	11,065	50.0 (14.1)	52.2 (14.4)	55.5 (15.2)	2.7 (0.2)	<0.0001
		>8.8MET-hours/week	11,130	52.6 (14.2)	55.8 (15.4)	59.4 (16.0)	3.3 (0.2)	<0.0001
		Test for interaction						0.02
rs4939883	18q45, LIPG	All women	22,763	54.2 (15.2)	53.0 (14.7)	51.6 (14.6)	−1.2 (0.17)	<0.0001
		≤8.8MET-hours/week	11,353	52.6 (14.8)	51.0 (13.9)	49.7 (14.0)	−1.4 (0.2)	<0.0001
		>8.8MET-hours/week	11,410	55.7 (15.3)	55.0 (15.1)	53.7 (15.0)	−0.9 (0.2)	0.0001
		Test for interaction						0.14

Values for HDL (high-density cholesterol) levels are mean (±SD).