Fig. 3.

Interactions of the individual domains of IF2_mt with components of the (A) small and (B) large ribosomal subunits. Helices of the 16S and 23S rRNAs are identified with h and H, respectively, whereas ribosomal proteins of the small and large subunits are prefixed by S and L, respectively. IF2_mt domains are color coded as in Fig. 2. Thumbnail to the left shows the overall orientation of the ribosome, with fitted atomic coordinates of E. coli 70S ribosome (35), IF2_mt (space-filling model), and the P/I tRNA (green ribbons).