Table 2.
Bactericidal activity, IgG, and IgM anti-B. pertussis Tohama I LPS (ELISA) elicited by different conjugates
| Conj no. | OS in a conjugate | No. of chains per BSA | Individual serum | IgG, EU | IgM, EU | Reciprocal bactericidal titers |
| 1 | B.p. Tohama I | 8 | 1786A | 3.6 | 3.2 | 20 |
| 2 | B.p. Tax113 | 25 | 2058H | 22.6 | 1.4 | 50 |
| 3 | B.p. Tax113 | 17 | 2059A | 9.4 | 4.2 | 100 |
| 3 | B.p. Tax113 | 17 | 2059E | 1.1 | 0.8 | 10 |
| 3 | B.p. Tax113 | 17 | 2059I | 13.8 | 9.5 | 750 |
| 4 | B.p. Tax113 | 11 | 2060A | 6.2 | 0.2 | 100 |
| 5 | B.b. RB50 core | 9 | 1787C | 9.6 | 1.7 | 500 |
| 5 | B.b. RB50 core | 9 | 1787G | 64.9 | 2.8 | 750 |
| 6 | B.b. RBwbmΔ | 19 | 2064A | 2.4 | 3.1 | 20 |
| 7 | B.b. RBwbmΔ | 11 | 2063A | 0.06 | 0.3 | <10 |
| 7 | B.b. RBwbmΔ | 11 | 2063C | 0.04 | 0.07 | <10 |
| 9 | B.b. RBB1a | 12 | 2093H | 38.4 | 13.9 | 750 |
| 9 | B.b. RBB1a | 12 | 2093J | 14.0 | 1.6 | 10 |
| 10 | B.b. RBA2b, F1 | 8 | 2152B | 5.3 | 0.6 | <10 |
| 11 | B.b. RBA2b, F2 | 9 | 2153D | 4.2 | 0.7 | 10 |
| 12 | B.b. RBA2b, F3 | 11 | 2154H | 4.1 | 0.2 | 10 |
| 13 | B.b. RBA2b, F4 | 9 | 2155D | 39.3 | 0.1 | 50 |
| 13 | B.b. RBA2b, F4 | 9 | 2155F | 2.1 | 3.8 | <10 |
| 13 | B.b. RBA2b, F4 | 9 | 2155H | 0.8 | 0.5 | <10 |
| PBS | — | 2156A | <0.01 | <0.01 | <10 |
Correlation coefficients between the reciprocal bactericidal titer and IgG, r = 0.66; IgM, r = 0.73; and IgG plus IgM, r = 0.74. *B.p., B. pertussis; B.b., B. bronchiseptica; –, not applied.