Table 3.
Mean (and SEM) Concentration (Picograms/Milligram) of Dopamine (DA), Dihydrophenylacetic Acid (DOPAC), Homovanillic Acid (HVA), and 3-Methoxytyramine (3-MT) and Metabolite/Transmitter Ratios in the Neostriatum of HDC-KO and Wild-Type Mice. P = HDC-KO Versus Wild-Type Mice t-Test for Independent Samples
| DA | DOPAC | HVA | 3-MT | DOPAC/DA | HVA/DA | 3-MT/DA | |
|---|---|---|---|---|---|---|---|
| HDC-knockout mice | |||||||
| Mean | 29,395.54 | 1666.32 | 1617.21 | 1174.81 | 0.0564 | 0.0551 | 0.0401 |
| SEM | 513.88 | 133.51 | 54.34 | 20.87 | 0.0042 | 0.0018 | 0.0011 |
| Wild-type mice | |||||||
| Mean | 28,463.30 | 1258.73 | 1591.82 | 1205.59 | 0.0443 | 0.0561 | 0.0424 |
| SEM | 354.75 | 133.10 | 61.29 | 37.89 | 0.0047 | 0.0023 | 0.0012 |
| P = | 0.160 | 0.054 | 0.775 | 0.528 | 0.088 | 0.769 | 0.213 |