Table 3.

Quantification of MCM colocalization with HSRs

Proteins expressed	Percent overall change in MCM enrichment
Cdt1 + pcDNA3	baseline Mcm7 or Mcm4
Cdt1 + HDAC1	+4% Mcm7
Cdt1 + HDAC11	−71% Mcm7
Cdt1 + HBO1-wt	0% Mcm7
Cdt1 + HBO1G485A	−42% Mcm7
Cdt1 + HDAC1	−12% Mcm4
Cdt1 + HDAC11	−79% Mcm4
Cdt1 + HBO1-wt	+8% Mcm4
Cdt1 + HBO1G485A	−54% Mcm4
Cdt1 + GST	baseline Mcm4
Cdt1 + Set8-HBD	−45% Mcm4

In each case, at least 100 transfected cells were scored. The results depicted are representative of at least two experiments performed for each condition, with similar outcomes. Errors for changes in MCM enrichment were 1–3% SD for each.