Table 2.
Sensitivity of P. vivax to chloroquine and WR99120; data are presented as geometric mean and median (95%CI) values of IC10, IC50 and IC90 obtained from 32 isolates.
| Drugs | Inhibitory Concentration (IC) | Geometric mean (nM) | Median (range) (nM) |
|---|---|---|---|
| Chloroquine | IC10 | 3.3 | 4.2 (0.2-7.1) |
| IC50 | 100.1 | 134.7 (1.1-264.9) | |
| IC90 | 2956.5 | 4134.9 (7.1-11535.0) | |
| WR99210 | IC10 | 4.9 | 5.7 (0.04-17.8) |
| IC50 | 112.7 | 139.9 (0.2-523.0) | |
| IC90 | 2585.0 | 3406.9 (1.1-15356.0) | |
IC 10, 50 and 90: drug concentrations which produced 10, 50 and 90% inhibition of parasite development, respectively, as compared to the control (analysed by nonlinear regression analysis using CalcuSyn™software).