Table 2.

The Effect of Age on the Apparent Volume of Distribution of Acetaminophen, Evans Blue, and Sucrose. Data Are Presented as Mean ± SD

	Young	Old
n	11	12
Apparent volume of distribution
Evans Blue (mL/g)	0.20 ± 0.06	0.29 ± 0.08*
Sucrose (mL/g)	0.31 ± 0.07	0.38 ± 0.07*
Acetaminophen (mL/g)	0.76 ± 0.11	0.74 ± 0.10
Ratio of apparent volume of distribution
Acetaminophen:sucrose	2.51 ± 0.26	1.95 ± 0.17**
Evans Blue:sucrose	0.65 ± 0.11	0.77 ± 0.14
Evans Blue:acetaminophen	4.00 ± 1.02	2.63 ± 0.51**

^*p < .05 young versus old,

^**p < .005 young versus old.