Table 2. Fitting Concentration-Response Data Yielded EC50, Emax and Hill Slope of WIN 55 212-2-Induced Depression of fEPSPs in NAc in Slices Obtained from Control, Sub-CUS, Control, and CUS Groups (n=6 for each group).
Emax (%) | EC50 (μM) | Slope | |
---|---|---|---|
Control (for sub-CUS) | 51.52±3.50 | 0.27±0.04 | 1.66±0.22 |
Sub-CUS | 48.57±3.40 | 0.26±0.08 | 1.79±0.39 |
Control (for CUS) | 53.19±2.90 | 0.30±0.06 | 1.36±0.16 |
CUS | 29.57±2.02*** | 0.29±0.06 | 1.21±0.10 |
***p<0.001 CUS vs control or sub-CUS.