Table 1. Baseline Characteristics.
| Early responders to Risperidone (N=144) | Early non-responders to Risperidone (N=378) | p-value | |
|---|---|---|---|
| Age (years), mean (SD) | 41.8 (10.9) | 41.9 (11.1) | 0.980 |
| Gender (F), n (%) | 58.0 (40.3) | 142.0 (37.6) | 0.615 |
| Ethnicity/race: | 0.191 | ||
| Caucasian, % | 51.4 | 42.3 | - |
| African descent, % | 37.5 | 47.6 | - |
| Hispanic, % | 10.4 | 8.5 | - |
| Diagnosis: | |||
| Schizophrenia/schizophreniform, % | 79.2 | 75.1 | 0.359 |
| Schizoaffective bipolar, % | 14.6 | 14.8 | 1.000 |
| Schizoaffective depression, % | 6.3 | 10.1 | 0.231 |
| Age at first schizophrenia episode (years), median | 24.0 | 23.0 | 0.297 |
| No. of previous episodes or exacerbations of schizophrenia in last 24 months, median | 2.0 | 3.0 | 0.019 |
| PANSS Total, mean (SD) | 93.9 (13.0) | 91.2 (13.8) | 0.030 |
| PANSS Positive, mean (SD) | 25.5 (4.1) | 23.7 (3.8) | <0.001 |
| PANSS Negative, mean (SD) | 22.9 (4.4) | 22.2 (5.2) | 0.111 |
| MADRS Total, mean (SD) | 15.9 (10.0) | 16.4 (8.7) | 0.759 |
| Weight (kg), mean | 90.5 | 88.5 | 0.409 |
MADRS, Montgomery–Asberg Depression Rating Scale; N, number of patients; n, number in group; PANSS, Positive and Negative Syndrome Scale.