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. 2008 Mar 19;35(5):1063–1072. doi: 10.1038/npp.2008.28

Table 2. Hormonal and Drug Level Measures during FEN Challenge.

Variables Non-patient comparison Depressed non-attempters Past attempters Future attempters p-valuea Contrastb
Baseline prolactin 10.1±3.9 9.0±3.8 8.1±3.8 7.5±3.9 0.43  
             
Peak change in prolactin 13.3±6.2 10.7±5.3 8.4±5.4 8.7±5.5 0.10  
             
Area under the curve prolactin 75.4±18.8 64.5±18.2 54.6±18.3 51.2±18.7 0.01 FA, PA<C
             
Baseline cortisol 12.5±4.8 14.7±4.7 12.3±4.7 15.4±4.8 0.24  
             
Peak change in cortisol 5.0±3.8 3.9±3.7 5.1±3.7 −0.3±3.8 0.01 FA<PA, N, C
             
Area under the curve cortisol 59.8±15.2 62.5±18.0 63.0±21.8 52.4±20.3 0.55  
             
Fenfluramine plus norfenfluramine levels 67.3±20.8 59.7±20.2 62.3±20.4 58.1±20.8 0.70  
a

Omnibus ANCOVA with age and sex as covariates for baseline measures, and with age, sex, and fenfluramine/norfenfluramine levels as covariates for peak change and area under the curve.

b

Tukey LSD post hoc test.