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Illustration of the Cortico-Stiato-Pallido-Thalamic loops related to the medial prefrontal network (on left) and the orbital prefrontal network (on right). Note that the two networks are related to parallel but distinct loops that involve adjacent parts of the cortex MD thalamus striatum and pallidum. Limbic structures such as the amygdala and hippocampus are primarily related to the medial network.
