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. 2010 Mar 3;35(7):1550–1559. doi: 10.1038/npp.2010.26

Figure 4.

Figure 4

Adenosine produced by CX3CL1-stimulated hippocampal cultures is reduced by ectonucleotidases inhibition with AOPCP. Hippocampal neurons were treated with 100 nM CX3CL1 or vehicle for 30 min, in the presence or in the absence of NBTI (1 μM) and AOPCP (1 μM), washed, and re-incubated in growth medium. After 6 h medium was analyzed by HPLC for adenosine content. Results are expressed as nmol of adenosine produced for mg of cellular proteins and significance is analyzed, for each condition, between CX3CL1-treated vs corresponding control samples. Data are the mean±SE from five independent quadruplicate experiments.