Figure 6.

The neuroprotective effect of BDNF and EPO is abolished in A₁R^−/− mice. Hippocampal neurons obtained from wt or A₁R^−/− mice were cultured for 11 days and then stimulated with Glu (100 μM, 30 min) in the presence or in the absence of BDNF (100 nM) or EPO (10 nM). Results represent the mean±SE of four independent duplicate experiments and are expressed as in Figure 5.