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. 2010 Mar 24;35(8):1734–1742. doi: 10.1038/npp.2010.39

Figure 2.

Figure 2

Improved performance of KAT II knock-out (KO) mice in an object exploration and recognition paradigm. (a) Locomotor activity (open field) and (b) object exploration (habituation to environment). Mutant mice habituated at a faster rate; (c) response to spatial change (object displacement). Compared with the baseline established in S4, KAT II KO animals spent more time than WT mice exploring the displaced object (DO) in sessions S5 and S6. Negative values reflect continued habituation in 21-day-old wild-type (WT) mice. Data are the mean±SEM of 16 animals per group. *p<0.05 vs WT controls.