Table 4. Association of rs2476601 (PTPN22*C1858T) polymorphism with presence of autoantibodies in patients with inflammatory polyarthritis (IP) and in the subset satisfying ACR classification criteria for rheumatoid arthritis (RA).
| Autoantibody at baseline | IP Cohort | RA subset | ||
| PTPN22*CC, n (%) | PTPN22*CT or PTPN22*TT, n (%) | PTPN22*CC, n (%) | PTPN22*CT or PTPN22*TT, n (%) | |
| RF present | 185 (74.0) | 65 (26.0) | 155 (74.5) | 53 (25.5) |
| RF absent | 442 (78.2) | 123 (21.8) | 231 (79.4) | 60 (20.6) |
| Comparison: p value | 0.19 | 0.20 | ||
| Anti-CCP present | 109 (68.5) | 50 (31.5) | 102 (69.4) | 45 (30.6) |
| Anti-CCP absent | 388 (78.1) | 109 (21.9) | 207 (82.1) | 45 (17.9) |
| Comparison: p value | 0.09 | 0.003 | ||
p Values are uncorrected.
ACR, American College of Rheumatology; CCP, cyclic citrinulated peptide; RF, rheumatoid factor.