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. 2010 May 19;35(9):1921–1931. doi: 10.1038/npp.2010.64

Table 5. Nicotinic Receptor Haplotypes Associated with Substance Dependence Traits.

SNPs Alleles (Freq case/control) Sample Phenotype P-value (global/haplotype)
rs3841324, rs684513 A–C (0.22/0.26) EA families OD 0.03/0.01
rs615470, rs578776 C–A (0.51/0.57) AA case–control AD 0.005/0.001
rs621849, rs16969968 A–A (0.05/0.08) AA case–control OD 0.008/0.01

Alleles shown represent the haplotype with the strongest effect on the trait of interest and the haplotype frequency in cases and controls.