Figure 10.

GS activity in retinal homogenates incubated at various pressures for 24 hours. There were no statistically significant changes in GS activity at 10 and 25 mm Hg. GS activity was significantly reduced after exposure to 50 or 75 mm Hg compared with that at 10 mm Hg. There was also a significant reduction of GS activity at 75 mm Hg compared with that at 50 mm Hg (P = 0.014, *P < 0.05 by Mann-Whitney U test). For these studies, we examined 10 control and 10 pressure-loaded retinal samples. NS, no significant difference. **P < 0.001 by Mann-Whitney U test versus control retina (incubated at 10 mm Hg).