Table 2.

Effects of Pressure Elevation to 75 mm Hg and 1.0 mM GA on NFLT or a Percentage of NFLT to Total Retinal Thickness, Density of Swollen Axons (Ax), and Damaged GCs and NDS

Condition (n)	Middle NFLT ± SE (μm) [P] NFLT ± SE (%) [P]	Central NFLT ± SE (μm) [P] NFLT ± SE (%) [P]	Middle Ax ± SE [P]	Middle GC ± SE [P]	Whole Retina NDS ± SE [P]
Control (5)	2.6 ± 0.8 [−]	13.5 ± 2.6 [−]	0.9 ± 0.5 [−]	0.1 ± 0.5 [−]	0.2 ± 0.1 [−]
	1.4 ± 0.5 [−]	6.1 ± 1.2 [−]
Pressure (5)	13.9 ± 4.7 [<0.001]*	22.9 ± 4.4 [<0.001]*	11.2 ± 2.5 [<0.001]*	9.7 ± 5.6 [<0.001]*	1.0 ± 0.5 [0.002]*
	9.0 ± 2.4 [<0.001]*	9.3 ± 1.6 [0.002]*
GA (5)	2.7 ± 0.9 [0.96]	12.9 ± 2.0 [0.82]	1.3 ± 0.7 [0.99]	10.0 ± 1.5 [<0.001]*	0.4 ± 0.4 [0.29]
	1.5 ± 0.7 [−]	5.8 ± 2.2 [0.93]
Pressure + GA (7)	15.4 ± 3.5 [<0.001]*	25.3 ± 8.9 [<0.001]*	38.3 ± 6.3 [<0.001]*	20.1 ± 5.6 [<0.001]*	3.6 ± 0.5 [<0.001]*
	9.8 ± 3.4 [<0.001]*	11.3 ± 5.4 [0.002]*

Axon and GC counts and calculation of probabilities are as described in Table 1. GA, glutamate.

^*Statistical significance was set at P <0.05.