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. 2010 Dec;51(12):6414–6423. doi: 10.1167/iovs.09-5127

Table 2.

Effects of Pressure Elevation to 75 mm Hg and 1.0 mM GA on NFLT or a Percentage of NFLT to Total Retinal Thickness, Density of Swollen Axons (Ax), and Damaged GCs and NDS

Condition (n) Middle NFLT ± SE (μm) [P] NFLT ± SE (%) [P] Central NFLT ± SE (μm) [P] NFLT ± SE (%) [P] Middle Ax ± SE [P] Middle GC ± SE [P] Whole Retina NDS ± SE [P]
Control (5) 2.6 ± 0.8 [−] 13.5 ± 2.6 [−] 0.9 ± 0.5 [−] 0.1 ± 0.5 [−] 0.2 ± 0.1 [−]
1.4 ± 0.5 [−] 6.1 ± 1.2 [−]
Pressure (5) 13.9 ± 4.7 [<0.001]* 22.9 ± 4.4 [<0.001]* 11.2 ± 2.5 [<0.001]* 9.7 ± 5.6 [<0.001]* 1.0 ± 0.5 [0.002]*
9.0 ± 2.4 [<0.001]* 9.3 ± 1.6 [0.002]*
GA (5) 2.7 ± 0.9 [0.96] 12.9 ± 2.0 [0.82] 1.3 ± 0.7 [0.99] 10.0 ± 1.5 [<0.001]* 0.4 ± 0.4 [0.29]
1.5 ± 0.7 [−] 5.8 ± 2.2 [0.93]
Pressure + GA (7) 15.4 ± 3.5 [<0.001]* 25.3 ± 8.9 [<0.001]* 38.3 ± 6.3 [<0.001]* 20.1 ± 5.6 [<0.001]* 3.6 ± 0.5 [<0.001]*
9.8 ± 3.4 [<0.001]* 11.3 ± 5.4 [0.002]*

Axon and GC counts and calculation of probabilities are as described in Table 1. GA, glutamate.

*

Statistical significance was set at P <0.05.