Figure 1.

Age-dependent changes of the TTase system in human lenses. Twenty-three normal human lenses, divided into second, third, fifth, sixth, and seventh decades, were used for the study. The data are shown as mean ± SD, with the number of lenses indicated as (n) in each decade. (A) TTase activity in mU/g lens wet weight. (B) GR activity in mU/g lens wet weight. (C) GSH level expressed as percentage of second decade. (D) Homogenates from 19-, 31-, 49-, 52-, 60-, and 77-year-old lenses were selected for immunoblot analysis for GR with a specific anti-GR antibody. The blot shown is a representative of three separate analyses.