Table 1.

Distribution of GSH-Dependent TTase System and NADPH-Dependent TRx System in Normal Human Lenses

	Young Lenses (20–35 years)		Old Lenses (55–70 years)
	Cortex	Nucleus	Cortex	Nucleus
GSH, μmol/g wwt	3.15 ± 0.48	2.44 ± 0.45*	1.70 ± 0.41†	1.14 ± 0.26*†
TTase, mU/g wwt	159 ± 20	185 ± 24	107 ± 24†	163 ± 24*
GR, U/g wwt	1.50 ± 0.86	1.58 ± 0.90	1.15 ± 0.34	0.91 ± 0.37
TR, mU/g wwt	211 ± 23	327 ± 51*	175 ± 25†	183 ± 55†
TRx, mU/g wwt	60.4 ± 15.0	75.2 ± 13.2	35.3 ± 5.2†	59.0 ± 13.3†

Nine young lenses (20–35 years) and 10 old lenses (55–70 years) were each dissected to cortical and nuclear fractions and analyzed for GSH level, TTase, GR, TR, and TRx activities. Data are expressed as mean ± SD.

^*P < 0.05 by comparing between the values of different portions.

^†P < 0.05 by comparing between the values of different ages.