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. Author manuscript; available in PMC: 2011 Mar 11.
Published in final edited form as: Lab Invest. 2010 May 10;90(7):1078–1090. doi: 10.1038/labinvest.2010.90

Figure 7.

Figure 7

Prostate tissue of TSP-1 KO has increased epithelial cell proliferation and MVD. Mouse prostate tissues were immunostained with anti-PCNA (a) and anti-factor VIII-related antigen (b) to assess proliferation and MVD, respectively. Representative tissue sections are shown. (c) The number of PCNA-positive and the total number of epithelial nuclei were counted at 100X to quantify proliferative activity. A minimum of 150 nuclei were counted for each mouse (n=6 per group). PCNA positivity is presented as a percent of the total number of nuclei counted; *P<0.007. (d) MVD quantified by counting vessels in 5 high power fields (HPF; 40X) for each mouse (n=6 per group; **P<0.00003).