Table 3.
Mapping reads from progeny and parent genomes to the reference genome.
Method of Sequencing | Parasite Name | Unique positions mapped3 | |
---|---|---|---|
Number (bps) | Percentage | ||
Sanger | HB3 | 21,326,115 | 91.7 |
Dd2 | 17,226,364 | 74.0 | |
454-Roche | 7C126 | 21,600,531 | 92.8 |
SC05 | 21,732,965 | 93.4 |
3Given as the percentage of the 3D7 genome coverage
All genomes had comparably similar distribution of the total bases sequenced (approximately 23 Mb) in terms of unique positions, however Dd2 had reads mapping to only 74% of the reference genome reducing the number of positions for screening alleles.