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. 2010 Nov 29;29(1):54–60. doi: 10.1200/JCO.2010.29.3183

Table 1.

Participant Demographics and Clinical Characteristics by Baseline HbA1C in a Cohort of US Breast Cancer Survivors

Characteristic HbA1C
P
< 6.5% (n = 2,818)
6.5% to 6.9% (n = 94)
≥ 7.0% (n = 91)
No. of Participants % No. of Participants % No. of Participants %
Demographics
    Age, years < .001
        Mean 50.6 54.1* 53.7*
        SE 8.79 8.64 8.23
    Ethnicity/race < .001
        White, non-Hispanic 2,436 86.4 72 76.6 61 67.0
        Nonwhite 382 13.6 22 23.4 30 33.0
    College educated 1,545 54.8 44 46.8 40 44.4 .017
    Married 1,989 71.1 57 62.0 59 65.6 .095
Breast cancer characteristics
    Cancer stage at diagnosis < .001
        I 1,109 39.4 33 35.1 25 27.8
        II 1,579 56.0 51 54.3 55 61.1
        IIIA 130 4.6 10 10.6 10 11.1
    Grade .978
        1 1,127 40.0 39 41.5 39 43.3
        2 1,018 36.1 31 33.0 29 32.2
        3 231 8.2 9 9.6 7 7.8
    Tumor receptor status .336
        ER positive/PR positive 1,733 62.9 62 66.7 56 62.9
        ER positive/PR negative 338 12.3 8 8.6 10 11.2
        ER negative/PR positive 119 4.3 1 1.1 7 7.9
        ER negative/PR negative 565 20.5 22 23.7 16 18.0
    Treatment
        Radiation 1,729 61.4 51 54.3 68 75.6 .008
        Chemotherapy 1,963 69.7 65 69.2 63 70.0 .991
        Lumpectomy 1,354 48.0 36 38.3 51 56.7 .044
        Mastectomy 1,463 51.9 58 61.7 39 43.3 .044
    Ever-use of antiestrogen 1,909 63.7 71 75.5 67 74.4 .128
    Years since diagnosis .901
        Mean 2.0 2.0 2.0
        SE 1.04 1.04 0.97
Other health measures
    Body mass index, kg/m2 < .001
        Mean 26.9 32.1* 34.2*
        SE 5.70 7.51 8.58
    Obese (≥ 30 kg/m2) 681 24.2 52 55.3 63 70.0 < .001
    Poor physical health 1,169 41.5 51 54.3 56 62.2 < .001
    Sedentary (< 150 MET-min/wk) 545 19.3 30 31.9 26 28.6 .001
    Menopausal status .026
        Premenopausal 328 11.7 3 3.2 5 5.6
        Postmenopausal 2,230 79.3 85 90.4 77 85.6
        Perimenopausal 256 9.1 6 6.4 8 8.9

Abbreviations: HbA1C, hemoglobin A1C; ER, estrogen receptor; PR, progesterone receptor; MET, metabolic equivalent.

*

P < .05 for comparison with HbA1C < 6.5% category.

P < .05 for comparison with HbA1C 6.5% to 6.9% category.