Table 1.
Characteristic | HbA1C |
P | |||||
---|---|---|---|---|---|---|---|
< 6.5% (n = 2,818) |
6.5% to 6.9% (n = 94) |
≥ 7.0% (n = 91) |
|||||
No. of Participants | % | No. of Participants | % | No. of Participants | % | ||
Demographics | |||||||
Age, years | < .001 | ||||||
Mean | 50.6 | 54.1* | 53.7* | ||||
SE | 8.79 | 8.64 | 8.23 | ||||
Ethnicity/race | < .001 | ||||||
White, non-Hispanic | 2,436 | 86.4 | 72 | 76.6 | 61 | 67.0 | |
Nonwhite | 382 | 13.6 | 22 | 23.4 | 30 | 33.0 | |
College educated | 1,545 | 54.8 | 44 | 46.8 | 40 | 44.4 | .017 |
Married | 1,989 | 71.1 | 57 | 62.0 | 59 | 65.6 | .095 |
Breast cancer characteristics | |||||||
Cancer stage at diagnosis | < .001 | ||||||
I | 1,109 | 39.4 | 33 | 35.1 | 25 | 27.8 | |
II | 1,579 | 56.0 | 51 | 54.3 | 55 | 61.1 | |
IIIA | 130 | 4.6 | 10 | 10.6 | 10 | 11.1 | |
Grade | .978 | ||||||
1 | 1,127 | 40.0 | 39 | 41.5 | 39 | 43.3 | |
2 | 1,018 | 36.1 | 31 | 33.0 | 29 | 32.2 | |
3 | 231 | 8.2 | 9 | 9.6 | 7 | 7.8 | |
Tumor receptor status | .336 | ||||||
ER positive/PR positive | 1,733 | 62.9 | 62 | 66.7 | 56 | 62.9 | |
ER positive/PR negative | 338 | 12.3 | 8 | 8.6 | 10 | 11.2 | |
ER negative/PR positive | 119 | 4.3 | 1 | 1.1 | 7 | 7.9 | |
ER negative/PR negative | 565 | 20.5 | 22 | 23.7 | 16 | 18.0 | |
Treatment | |||||||
Radiation | 1,729 | 61.4 | 51 | 54.3 | 68 | 75.6 | .008 |
Chemotherapy | 1,963 | 69.7 | 65 | 69.2 | 63 | 70.0 | .991 |
Lumpectomy | 1,354 | 48.0 | 36 | 38.3 | 51 | 56.7 | .044 |
Mastectomy | 1,463 | 51.9 | 58 | 61.7 | 39 | 43.3 | .044 |
Ever-use of antiestrogen | 1,909 | 63.7 | 71 | 75.5 | 67 | 74.4 | .128 |
Years since diagnosis | .901 | ||||||
Mean | 2.0 | 2.0 | 2.0 | ||||
SE | 1.04 | 1.04 | 0.97 | ||||
Other health measures | |||||||
Body mass index, kg/m2 | < .001 | ||||||
Mean | 26.9 | 32.1* | 34.2*† | ||||
SE | 5.70 | 7.51 | 8.58 | ||||
Obese (≥ 30 kg/m2) | 681 | 24.2 | 52 | 55.3 | 63 | 70.0 | < .001 |
Poor physical health | 1,169 | 41.5 | 51 | 54.3 | 56 | 62.2 | < .001 |
Sedentary (< 150 MET-min/wk) | 545 | 19.3 | 30 | 31.9 | 26 | 28.6 | .001 |
Menopausal status | .026 | ||||||
Premenopausal | 328 | 11.7 | 3 | 3.2 | 5 | 5.6 | |
Postmenopausal | 2,230 | 79.3 | 85 | 90.4 | 77 | 85.6 | |
Perimenopausal | 256 | 9.1 | 6 | 6.4 | 8 | 8.9 |
Abbreviations: HbA1C, hemoglobin A1C; ER, estrogen receptor; PR, progesterone receptor; MET, metabolic equivalent.
P < .05 for comparison with HbA1C < 6.5% category.
P < .05 for comparison with HbA1C 6.5% to 6.9% category.