Table 3.

Multivariate HRs of Overall Survival and Disease-Free Survival According to Baseline HbA1C in a Cohort of US Breast Cancer Survivors With a Median of 10.3 Years of Survival Follow-Up and a Median of 7.3 Years of Follow-Up for Additional Breast Cancer Events (N = 3,003)

HbA1C Category, %	No. of Patients	No. of Deaths	Overall Survival			No. of Breast Cancer Events	Disease-Free Survival
			HR	95% CI	P		HR	95% CI	P
< 6.5	2,818	368	1.00*		—	466	1.00*		—
6.5-6.9	94	18	1.33	0.82 to 2.16	.25	18	1.11	0.69 to 1.80	.67
≥ 7.0	91	28	2.35	1.56 to 3.54	< .001	19	1.26	0.78 to 2.02	.34

NOTE. Analysis was adjusted for stage, grade, age, ethnicity, education, physical activity, and physical health.

Abbreviations: HR, hazard ratio; HbA1C, hemoglobin A1C.

^*Reference category.