Table 3.

Biomarker Analyses

Biomarker	No.	Analysis
		Median	Lower Quartile	Upper Quartile
pERK*
Pretreatment	37	1,553.09	1,082.47	1,931.40
Post-treatment	36	1,238.93	874.41	1,740.80
ΔpERK†	32	23.78	−756.57	442.46
ERK (pretreatment)‡	60	0.89	0.16	1.89
Raf (pretreatment)‡	60	0.87	0.13	1.90

Abbreviation: pERK, phosphorylated ERK.

^*pERK as measured by lysate arrays.

^†Post-treatment pERK minus pretreatment pERK.

^‡ERK and Raf immunohistochemistry H score.