Table 2. Reduction of bacterial load in a murine colonization model by immunization with recombinant B. abortus AfuA, D15, or Hia.
| Time (days)Post-infection | AdjuvantOnly | AfuA | D15 | Hia | p value | Logreduction |
| 0 | - | - | - | - | ||
| 7 | 2.51×106 | ND | ND | ND | ||
| (+/− 3.34×105) | ||||||
| 14 | 9.94×107 | 2.89×107 | 4.40×107 | 1.88×107 | ||
| (+/− 2.17×107) | (+/− 1.78×107) | (+/− 2.23×107) | (+/− 7.02×106) | |||
| 21 | 2.64×106 | 6.53×104 | 1.23×105 | 4.20×104 | <0.001 | 1.41 |
| (+/− 8.57×105) | (+/− 5.38×104) | (+/− 8.05×104) | (+/− 2.81×104) | (D15) | ||
| 28 | 1.38×105 | 1.59×104 | 1.50×104 | 2.89×104 | <0.05 | 1.91 |
| (+/− 8.37×104) | (+/− 9.31×103) | (+/− 9.08×103) | (+/− 1.27×104) | (Hia) |