Skip to main content
. 2011 Mar 11;6(3):e17531. doi: 10.1371/journal.pone.0017531

Figure 5. Induction of tendon cell-related genes by BMP-12 in rat BM-MSC implants in calcaneal tendon in vivo.

Figure 5

Samples were collected as described in Methods and Materials. mRNA levels were determined by qRT-PCR and normalized against samples of the non-BMP-12-treated group. The gene expression of all experimental groups was determined as fold changes relative to native tendon samples. While unseeded implants expressed minimal Scx, Tnmd, Col I, and Tn-C, BMP-12-treated implants had significantly increased expression of these genes compared to non-BMP-12-treated implants. Data are expressed as mean ± S.D. (n = 3). * represents p<0.05.