EtOH increases BBB permeability and decreases BBB electrical resistance: Permeability of sodium fluorescein (NaFl; 5 μM)/Evans Blue (EB;5 μM) across the BBB is shown in a, b acute EtOH exposure (single dose of 650 mM) and c, d chronic EtOH administration (4%, v/v). e TEER of hBECs monolayers following treatment with various test compounds (n=3). TEER was measured at 400 Hz in 10-min intervals for 12 h. The treatments were started after stable resistance was reached for 2 h.*p<0.05, **p<0.01, and ***p<0.001 statistically significant compared with control