Fig. 2.
Proteins containing Lys-48-linked poly-ubiquitin accumulate in MS-WM and MS-GM. (A) Representative immunoblots from homogenates of the brain WM and GM areas of control and MS patients developed with antibodies against Lys-48 poly-ubiquitin. (B) The relative levels of proteins containing Lys-48 ubiquitin were calculated by dividing the whole lane intensity on the immunoblots by that of the corresponding coomassie blue stained lane. Each point represents a patient and the horizontal bar is the average. *p<0.05. Other symbols are as in Fig. 1.