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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Biochemistry. 2010 Jun 1;49(21):4516–4523. doi: 10.1021/bi1003684

Fig 5. Effect of incorporation of β-spectrin peptide that binds to ankyrin (βIR(14-15) on membrane mechanical stability and spectrin dimer- tetramer equilibrium.

Fig 5

A. membrane mechanical stability of the resealed ghosts was measured by ektacytometry. Membrane stability, expressed as the rate of decline in deformability index, DI, diminishes (decay curve displaced toward shorter times) with increasing concentrations of peptide incorporated into cells. B. Densitometric evaluation of native electrophoretic gels of spectrin extracted from cells treated with peptide, showing partial dissociation of spectrin tetramers.