Table 2. Changes in severity of BMLs, synovitis, and effusion in relation to severity of frequent knee pain.
| Structural Lesions | Severity of Frequent Knee Pain at a Clinic Visit | Crude OR (95% CI) | Adjusted OR (95% CI)* | ||
|---|---|---|---|---|---|
| No frequent knee pain | Mild/moderate | Severe/extreme | |||
| BMLs | |||||
| 0 | 177 | 132 | 26 | 1.0 (ref) | 1.0 (ref) |
| 1 | 140 | 99 | 20 | 1.2 (0.8, 1.8) | 1.3 (0.8, 2.1) |
| 2 | 103 | 74 | 14 | 1.3 (0.8, 2.2) | 1.2 (0.7, 2.0) |
| 3 | 90 | 65 | 17 | 1.4 (0.8, 2.4) | 1.4 (0.8, 2.4) |
| 4 | 53 | 53 | 11 | 2.1 (1.1, 4.0) | 1.9 (1.0, 3.8) |
| 5-6 | 72 | 74 | 20 | 2.7 (1.4, 5.2) | 2.2 (1.1, 4.4) |
| 7-18 | 71 | 64 | 21 | 3.0 (1.5, 6.0) | 2.2 (1.0, 4.7) |
| P for trend | 0.047 | ||||
| Synovitis | |||||
| 0 | 251 | 180 | 39 | 1.0 (ref) | 1.0 (ref) |
| 1 | 259 | 211 | 57 | 1.7 (1.0, 2.7) | 1.3 (0.8, 2.3) |
| 2 | 111 | 83 | 18 | 1.8 (0.9, 3.4) | 1.5 (0.7, 2.8) |
| 3-6 | 85 | 87 | 15 | 2.5 (1.1, 5.6) | 2.4 (1.0, 5.6) |
| P for trend | 0.052 | ||||
| Effusions | |||||
| 0 | 254 | 191 | 45 | 1.0 (ref) | 1.0 (ref) |
| 1 | 306 | 220 | 51 | 1.2 (0.8, 1.9) | 0.9 (0.6, 1.5) |
| 2-3 | 146 | 150 | 33 | 2.7 (1.5, 4.8) | 1.6 (0.9, 3.0) |
| P for trend | 0.059 | ||||
*
Odds ratio (OR) for a specific structural lesion was mutually adjusted for other two structural lesions in addition to BMI, knee injury, mental health status, and maximal cartilage morphology score.