Table 2.
Region | Mean common volume | Mean volume difference | % volume difference | T-value | P-value |
95% confidence interval |
||
---|---|---|---|---|---|---|---|---|
ICC | Low | High | ||||||
L cerebral cortex | 246.1 | 63.9 | 26.0 | 15.6 | <0.0001 | 0.50 | 0.30 | 0.66 |
R cerebral cortex | 246.7 | 62.7 | 25.4 | 14.9 | <0.0001 | 0.47 | 0.27 | 0.64 |
L cerebral white matter | 215.0 | 16.3 | 7.6 | 6.4 | <0.0001 | 0.81 | 0.71 | 0.88 |
R cerebral white matter | 216.8 | 14.0 | 6.5 | 6.1 | <0.0001 | 0.85 | 0.77 | 0.90 |
L Lat Vent | 12.7 | 0.2 | 1.4 | 1.6 | 0.11 | 0.99 | 0.99 | 1.00 |
R Lat Vent | 11.0 | −0.1 | −0.5 | −0.5 | 0.61 | 0.99 | 0.98 | 0.99 |
L thalamus | 6.3 | 0.7 | 11.2 | 10.5 | <0.0001 | 0.77 | 0.66 | 0.85 |
R thalamus | 6.4 | 0.8 | 12.0 | 12.0 | <0.0001 | 0.75 | 0.63 | 0.84 |
L hippocampus | 3.6 | 0.0 | −0.2 | −0.1 | 0.92 | 0.55 | 0.37 | 0.70 |
R hippocampus | 3.8 | 0.0 | −1.3 | −0.9 | 0.37 | 0.61 | 0.43 | 0.74 |
L amygdala | 1.6 | 0.0 | −0.8 | −0.4 | 0.67 | 0.57 | 0.38 | 0.71 |
R amygdala | 1.6 | −0.1 | −6.2 | −3.3 | 0.001 | 0.52 | 0.33 | 0.68 |
L caudate | 3.4 | −0.1 | −1.7 | −1.5 | 0.13 | 0.82 | 0.73 | 0.88 |
R caudate | 3.5 | 0.1 | 2.2 | 1.8 | 0.07 | 0.79 | 0.68 | 0.86 |
L putamen | 4.6 | −0.2 | −3.4 | −2.2 | 0.029 | 0.56 | 0.38 | 0.70 |
R putamen | 4.6 | 0.1 | 1.6 | 1.2 | 0.25 | 0.61 | 0.44 | 0.74 |
L pallidum | 1.8 | −0.3 | −15.1 | −8.0 | <0.0001 | 0.52 | 0.32 | 0.67 |
R pallidum | 1.7 | −0.2 | −10.9 | −5.0 | <0.0001 | 0.48 | 0.28 | 0.64 |
L accumbens area | 0.53 | 0.1 | 17.1 | 4.6 | <0.0001 | 0.26 | 0.03 | 0.47 |
R accumbens area | 0.54 | 0.1 | 13.1 | 3.0 | 0.004 | 0.20 | −0.04 | 0.41 |
Note: The test statistic is given for the hypothesis that the average volume difference is 0, as an indicator of difference in the measurement. Positive values indicate the CMA volume is greater than the FreeSurfer volume. The ICC is given for the assumption of the consistency of volumes between methods (see text for details).
Abbreviations: CMA, Center for Morphometric Analysis; ICC, intraclass correlation coefficient.