TABLE 1.
Treatment | N | LY-171555-induced activity (counts/150 min) |
---|---|---|
Saline | 7 | 2669 ± 349 |
Reserpine + α-methyltyrosine | 6 | 972 ± 178b |
Rats were habituated to the chamber for 1 h before LY-171555 (1 mg/kg) administration. The α-methyltyrosine (40 mg/kg) was given just prior to the habituation period and 23 h after reserpine (2.5 mg/kg, subcutaneously). See fig. 3 for effects of dopamine antagonists.
P < 0.01 when compared to saline.