Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
mTORC1 is Selectively Impaired in the Rheb1f/f, Nes-cre KO Brain.
(A) Western blots show a drastic reduction in mTORC1 activity in the 4-wk old Rheb1f/f, Nes-cre (hereafter, KO) brain while the total level of S6 is not altered.
(B) Western blots show significant upregulation of mTORC2 activity in the 4-wk old Rheb1 KO brain and concurrent upregulation of the activity of signaling components upstream of Rheb1 (pAKT308 and pTSC2).
