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Models for Ypt6p/Ric1p-mediated retrieval of TGN membrane proteins. Dotted arrows indicate possible Ypt6-dependent pathways. CGN-targeted vesicles containing Gos1p and possibly Ykt6p may originate from the prevacuolar endosome compartment (PVC; pathway 1) or from the TGN (pathway 2). Ykt6p may act as part of a Sed5p t-SNARE rather than as a vesicle-associated v-SNARE. See text for details.
