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. Author manuscript; available in PMC: 2011 Nov 4.
Published in final edited form as: Neuron. 2010 Nov 4;68(3):409–427. doi: 10.1016/j.neuron.2010.09.043

Figure 7. Hypoxic Brain Tissue Changes in Pericyte-Deficient Mice.

Figure 7

(A) Confocal analysis of hypoxyprobe-1 (pimonidazole)-positive hypoxic (O2 <10 mm Hg) tissue in the hippocampus of 8 month old Pdgfrβ+/+, Pdgfrβ+/− and F7 mice.

(B) Quantification of hypoxyprobe-1-positive area expressed as a percentage of total tissue area in the cortex and hippocampus of 6–8 month old Pdgfrβ+/+, Pdgfrβ+/− and F7 mice. A total of 36 and 24 randomly chosen fields (420 × 420 μm) from 6 non-adjacent cortical and hippocampal sections, respectively, were analyzed per mouse. Mean ± s.e.m., n=6 mice per group; *p<0.05 or **p<0.01 by one-way ANOVA. (See Fig. S7).