Table 1.
Demographics and Clinical Characteristics of Participating Patients
| Characteristic | DC Dose Level (No. of DC/dose) |
Total No. of Patients (n = 22) | % | |
|---|---|---|---|---|
| 1 (1 × 107) | 2 (3 × 107) | |||
| Received at least one vaccine | 11 | 11 | 22 | |
| Completed at least four vaccines | 10 | 9 | 19 | 86 |
| Female (received at least four vaccines) | 5 | 4 | 9 | 47 |
| Median age, years | 52 | 46 | 48 | |
| Range | 37-71 | 28-63 | 28-71 | |
| Tumor histology | ||||
| AA | 3 | 2 | 5 | 23 |
| AO | 1 | 2 | 3 | 14 |
| AOA | 1 | 0 | 1 | 4 |
| GBM | 6 | 7 | 13 | 59 |
| No. of previous recurrences | ||||
| 0 | 7 | 4 | 11 | 50 |
| 1 | 2 | 5 | 7 | 32 |
| 2 | 2 | 2 | 4 | 18 |
Abbreviations: DC, dendritic cells; AA, anaplastic astrocytoma; AO, anaplastic oligodendroglioma; AOA, anaplastic oligoastrocytoma; GBM, glioblastoma multiforme.