Figure 4.
Low dose SST produces “quantal slowing” of fictive inspiration. A, Integrated fictive inspiratory output of C4 before (control) and after bath application of 10−13 m somatostatin. B, Instantaneous inspiratory period before and during SST application in same preparation as A. Note the clustering of periods at near-integer multiples of the control baseline period. C, Period histograms of four different preparations in the presence of 10−13 m SST showing “quantal” slowing. Tn, Duration of a cycle; Tref, duration of a control cycle.