TABLE 4.
Body weights, measured before starting injections and at the end of injections, and serum calcium, measured 3 h after last PTH injection, in 6-month old male COX-2 WT and KO mice injected with PTH (80 μg/kg) or vehicle for 22 days.
| Parameter | COX-2 WT | COX-2 KO | ||
|---|---|---|---|---|
| Vehicle | PTH | Vehicle | PTH | |
| Weight at start | 47.4±1.8 | 47.0±1.7 | 43.4±1.4 | 41.9±2.0 |
| Weight at end | 46.2±1.8 | 46.4±1.6 | 42.7±1.4 | 42.6±2.0 |
| Serum calcium | 10.2±0.2 | 11.3±0.3a | 10.6±0.2 | 11.4±0.2a |
Data are means ± SEM for n=11-13 mice.
Significant effect of PTH, p<0.05.