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. Author manuscript; available in PMC: 2011 Mar 14.
Published in final edited form as: Biochem J. 2009 Apr 15;419(2):377–385. doi: 10.1042/BJ20082082

Figure 3. I1514A, G1516A, F1518A and N1522A substitutions alter sodium channel sensitivity to a range of structurally different pyrethroid insecticides.

Figure 3

The percentage of channel modification by pyrethroids was determined using the method described in the Experimental section. Chemical structures of pyrethroids are shown above each histogram. The concentration of pyrethroid used in determining the percentage of channel modification was 0.1 µM (hatched bars), 1 µM (closed bars) or 10 µM (open bars), depending on the sensitivity of the mutant channels.