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. Author manuscript; available in PMC: 2011 Sep 15.
Published in final edited form as: Free Radic Biol Med. 2010 Jun 22;49(6):1036–1045. doi: 10.1016/j.freeradbiomed.2010.06.016

Table 1.

Initial and final body weights and blood glucose concentrations in control and diabetic mice maintained with and without CDC inhibitor treatment (Experiment 2) or fed normal chow or high-fat diet (Experiment 3).

Variable Body weight (g) Blood glucose (mmol/l)
Group Initial Final Initial Final
EXPERIMENT 2
Control 25.8 ± 0.6 38.5 ± 1.3 9.4 ± 0.7 8.7 ± 0.3
Control + CDC 25.4 ± 0.5 36.6 ± 1.4 9.4 ± 0.4 9.3 ± 0.3
Diabetic 25.1 ± 0.4 27.7 ± 0.5** 15.7 ± 1.2** 27.7 ± 1.1**
Diabetic + CDC 25.5 ± 0.5 26.8 ± 0.6** 16.1 ± 1.5** 28.9 ± 1.0**
EXPERIMENT 3
Wild-type, NC 24.8 ± 0.7 35.4 ± 1.0 8.4 ± 0.6 9.3 ± 0.6
Wild-type, HFD 25.0 ± 0.6 46.0 ± 1.6** 9.1 ± 0.7 9.5 ± 0.7
 LO-/-, NC 25.6 ± 0.7 34.9 ± 1.2 9.0 ± 0.5 9.4 ± 0.4
 LO-/-, HFD 25.3 ± 0.5 44.7 ± 1.5** 8.6 ± 0.4 9.2 ± 0.5

Data are expressed as Means ± SEM. n = 24 per group in Experiment 3 and at the beginning of the study in Experiment 2. n = 10-12 per group after the beginning of CDC treatment in Experiment 2.

**

p < 0.01 vs non-diabetic control group (Experiment 2) and vs mice fed normal chow (Experiment 3).

NC – normal chow, HFD- high-fat diet.